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Research in molecular entomology
New awards
July 2005
  
The TDR Committee on Molecular Entomology (BCV) [workplan] met in Geneva, Switzerland, in May 2005, to deliberate and recommend projects for funding by TDR. The projects listed below were selected from among a large number of applications received from investigators worldwide.

New grants in molecular entomology

These grants will be funded for one year in the first instance, and for additional year, if sufficient progress is made in the first year towards reaching the scientific objectives, and if sufficient funds are available.

Project
ID
Principal Investigator   Institution   Project Title Funding in US$
A50334 Serap Aksoy Yale University School of Medicine, Dpmt of Epidemiology & Public Health, New Haven Connecticut, USA   Glossina developmental stage specific EST project 5,000
A50363 Christopher Bosio Colorado State Univ., Dpmt of Microbiology, Immunology & Pathol., Fort Collins, Colorado, USA Population genetics and vector competence for dengue-2 virus of Aedes aegypti in Senegal  26,500
A50241 George K. Christophides European Molecular Biology Laboratory, Heidelberg, Germany   Effects of the Anopheles gambiae immune system on the transmission of human malaria parasite Plasmodium falciparum  39,998
A50333 Nancy M. DuTeau Colorado State University, Fort Collins, Colorado, USA Biology of disease vectors course - 2006  50,000
A50335 Paul Eggleston Keele University School of Life Sciences, Keele Staffordshire, UK    High efficiency, site-directed engineering of the mosquito genome for the control of vector-borne disease  40,000
A50299 Gabriella Irene Gibson University / Greenwich, Natural Resources Institute, Chatham Kent, UK Field & laboratory investigation of swarming and mating activities in the Anopheles gambiae species complex  40,000
A50331 Winston A Hide University of Western Cape, South African National Bioinformatics Institute (SANBI), Bellville, South Africa    Consolidation and functional annotation of reconstructed transcripts for Glossina  10,000
A50232  Yvonne-Marie Linton The Natural History Museum, Mosquitoes Progr., Department of Entomology, London, UK Molecular systematics and vector incrimination of the Oswaldoi group (Anopheles, Nyssorhynchus) in Latin America   39,906
A50256  Jesus Martinez Barnetche Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico    Functional genomic analysis of Anopheles albimanus immune response to infection with bacteria and Plasmodium vivax   40,000
A50375 Philippe Solano Institut de Recherche pour le Développement, Bobo Dioulasso, Burkina Faso  Full length cDNA sequencing of Glossina palpalis  15,000
A50340 Kenneth D. Vernick University of Minnesota, Center for Microbial and Plant Genomics, St Paul, Minnesota, USA    Breeding and analysis of new malaria resistant lines of Anopheles gambiae 38,359
A50230 Joao Pedro S. da Silva Pinto Centro de Malaria e outras Doenças Tropicais/IHMT, Lisbon, Portugal  Malaria vectors in islands, studies on genetic isolation   25,778
A50303 Mario A.C. Silva-Neto Univers. Federal do Rio de Janeiro, Centro de Ciências da Saude, Instit. Bioquim. Médica, Rio de Janeiro, Brazil     Phosphoproteome of malaria-infected mosquito midgut 8,500

Renewed grants in molecular entomology

These projects were funded in 2004 and are now being renewed for a further year following the successful progress made towards meeting the objectives during the first year.

Project
ID
Principal Investigator   Institution   Project Title Funding in US$
A30272  Nora Jessie Besansky University of Notre Dame, Dept. Biological Sciences, Notre Dame, Indianapolis, USA   The 2Rj inversion breakpoint of An. gambiae: molecular diagnosis and characterization. 30,501
A20338 George Dimopoulos  John Hopkins Univ., Bloomberg School of Public Health, Malaria Research Unit, Baltimore, MD, USA  Genome expression analysis of mosquito salivary gland function and characterization of specific promoters  40,000
A20269 Qi Gao Jiangsu Institute of Parasitic Diseases, Malaria Division, Meiyuan, Wuxi Jiangsu, P. Republic of China   Identification of Anopheles sinensis and Anopheles anthropophagus and their role in malaria transmission in China  29,400
A30345 Luna Kamau Kenya Medical Research Institute, Centre for Biotechnol., Research and Development, Nairobi, Kenya  Population genetic structure and development of insecticide resistance in An. gambiae s.1. and An. funestus in Kenya  36,460
A20330 Lizette Koekemoer National Health Laborat. Services, Vector Control Reference Unit, Johannesburg, South Africa   The role of mono-oxygenases in insecticide resistant Anopheles funestus Giles  17,950
A30328  Elena A. Levashina CNRS: UPR 9022, Institute of Molecular and Cellular Biology, Strasbourg, France Recognition and signalling during Plasmodium infection in the mosquito Anopheles gambiae  30,000
A30346  Thanasis Loukeris Institute of Molecular Biology and Biotechnology (IMBB), Crete, Greece    A study of Anopheles and Plasmodium proteases focusing on ookinete/midgut interactions  40,000
A30307  Colin Anthony Malcolm Queen Mary University of London, School of Biological Sciences, London, UK  Microsatellite & retroposon polymorphism in Anopheles arabiensis at the edge of its distribution in northern Sudan  40,000
A10424  Ana Maria Peralta De Merida Universidad del Valle de Guatemala, Guatemala, Guatemala   Population genetics of Aedes aegypti in Chiapas (Mexico) and Central America  11,577
A40190  Hilary Ranson Vector Research Group, Liverpool School of Tropical Medicine, Liverpool, UK  A functional genomics approach to improving insecticide resistance detection in Anopheles gambiae 2,700
A30289  Guiseppe Saccone Dipartimento di Genetica, Biologia Generale e Moleculare, Naples, Italy    Identification of sex determining genes in Aedes aegypti and improvement of transgene vectors to study their functions  36,500
A30350  N'Fale Sagnon Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso Génétique et comportement des membres du complexe Anopheles gambiae au Burkina Faso 34,350
A20315 Rosemary C. Sang Kenya Medical Research Institute, Centre for Virus Research, Nairobi, Kenya    A comparative study of populations of Aedes aegypti in dengue endemic and non-endemic areas of Kenya  29,703
A40198  Catherine Walton University of Manchester, Faculty of Life Sciences, Manchester, UK Genetic population structure and gene flow in Aedes aegypti mosquitoes in South-East Asia 40,000

TDR expresses sincere gratitude to Members of the Steering Committee and external reviewers for their critical assessment and contributions to the selection process.

TDR would like to thank, those investigators who were not funded. A large number of projects were reviewed but only a few were selected due to the high competitive selection process. TDR wishes to encourage these investigators to continue their good work and to re-compete next year (see deadline for submission of new applications).

Detailed information on funding and how to apply for support from the Committee on Molecular Entomology (BCV) can be obtained from the following web site http://www.who.int/tdr/grants.

TDR contact: Dr Y Toure

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