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Research in pathogenesis and applied genomics
New awards
July 2004
  
The TDR Committee on Pathogenesis and Applied Genomics (PAG) [workplan] met in Accra, Ghana, to deliberate and recommend projects for funding by TDR. The projects listed below were selected from among a large number of applications received from investigators worldwide.

New grants in pathogenesis and applied genomics

These grants will be funded for 12 months in the first instance, and for an additional 1 year if sufficient progress is made in the first 12 months toward reaching the scientific objectives, and if sufficient funds are available.

Project
ID
Principal Investigator   Institution   Project Title Funding in US$
A40098 Maria Isabel Nogueira Cano Universidade Estadual de Campinas (UNICAMP) Sp, Brazil   Functional & biochemical characterization of the putative Leishmania telomeric proteins LaRpa-1 and LaRbp38 30,000
A40101 Ricardo Tostes Gazzinelli Universidade Federal de Minas Gerais, Depto de Bioquimica e Imunologia
Belo Horizonte, Brazil
  Roll of Tll-like receptors in malaria pathogenesis 35,000
A40089 Emmanuela Handman Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia   A new model to study the role of innate immunity in the pathophysiology of Leishmania major infection 35,000
A40204 Zahra Hasan Aga Khan University, Karachi, Pakistan    Chemokines as immunopathological markers in tuberculosis infections - pulmonary and extra-
pulmonary
35,000
A40297 Maria de Fatima Horta Universidade Federal de Minas Gerais, Instituto de Ciencias Biologicas, Belo Horizonte, Minas 
Gerais, Brazil
  Molecular characterization of leishporin, a pore-forming protein of Leishmania amazonensis 34,260
A40278 Maria Susana Leguizamon Universidad Nacional de General San Martin, San Martin, Ba, Argentina    Differential expression of virulence factors and human infection by the main parasite lineages of Trypanosoma cruzi 20,000
A40234 Mohamed Hechmi Louzir Institut Pasteur de Tunis, Tunis, Tunisia   Host -parasite relationships: induction of regulatory immune mechanisms as expression of wild Leishmania major virulence 35,000
A40263 Carlos Andre O. Ricart Universidade de Brasilia, Departmento de Biologia Celular, Brazil    Trypanosoma cruzi proteomics initiative 31,750
A40062 Worachart Sirawaraporn Mahidol University, Department of Biochemistry, Thailand   Exploring the non-active site region of Plasmodium falciparum DHFR-TS as a molecular target for inhibitor design 35,000
A40270 Martha Carolina Vergel Monsalve Centro Internacional de Entrenamiento e Investigaciones Medicas (CIDEIM), Cali, Valle, Colombia    Identification of the fbp ABC gene regulador of Mycobacterium tuberculosis as a novel drug target 10,000

Renewed grants in pathogenesis and applied genomics

These projects have been funded for one year and are now being renewed for a further year following the successful progress made towards meeting the objectives during the first year. 

Project
ID
Principal Investigator   Institution   Project Title Funding in US$
A10311 Hannah Opokua Akuffo Karolinska Institute, Microbiology and Tumorbiology, Stockholm, Sweden   Innate immunity to human leishmaniasis and its influence on vaccine outcome 35,000
A10349 Hanna Opokua Akuffo Karolinska Institute, Microbiology and Tumorbiology, Stockholm, Sweden The role of apoptosis in the pathogenesis of human leishmaniasis 35,000

TDR expresses sincere gratitude to members of the Steering Committees and to external reviewers for their critical assessment and contributions to the selection process.

TDR would also like to thank those investigators who were not funded. A large number of projects were reviewed but only a few selected due to the highly competitive selection process. TDR wishes to encourage these investigators to continue their good work and to re-compete next year (see deadline for submission of new applications).

Detailed information on funding and how to apply for support from the Committee on Pathogenesis and Applied Genomics (PAG and the South-South Initiative can be obtained from the following web site http://www.who.int/tdr/grants, http://ssi-tdr.net and from Dr Ayoade M. J. Oduola, Manager Pathogenesis and Applied Genomics Committee

TDR contact: Dr A Oduola

Reference

* For more information about South-South collaboration see: www.ssi-tdr.net

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