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Vaccine Discovery 
Research
New awards
May 2003
  
The TDR Vaccine Discovery Research Committee met in Geneva, Switzerland, May 2003, to deliberate and recommend projects for funding by TDR. The projects listed below were selected from among a large number of applications received from investigators worldwide.

New grants in vaccine discovery research 

Project
ID
Principal Investigator   Institution   Project Title Funding in US$
A30118 Professor Virander Singh Chauhan International Centre for Genetic Engineering and Biotechnology, New Delhi, India   Study of immunogenicity & proteoctive efficacyof rodent homolgs of P. falciparum Merozoite surface protein-9 36,200
A30134 Dr Ikram Guizani Institut Pasteur de Tunis, Tunis, Tunisia   Comparative structure – function analysis of LelF, a unique Leishmania protein bearing properties of a Th 1 type adjuvant 35,000
A30125 Dr Lim Miao Fourth Military Medical University, Xian China   Protective immune response induced by the combination of P. falciparum MSP1 and AMA+ based protein, DNA & rMVA vaccine 23,000
A30158

 

Dr Abhy Satoskar

 

Ohio State University, Colombus, USA   Development of amastigote-specific gene chimeric vaccine against visceral leishmaniasis 15,000

 

A30137 Professor Allen Wilson University of Yourk, Department of Biology York, United Kingdom   Protective antigens in animal models of schistosome immunity 40,000
A30112 Dr Michelle Wykes Queensland Istitute of Medical Research, Brisbane, Queensland, Australia   Regulation of B and T cell memory to MSP1-19 38,208
A30133 Dr Seddikeh Zakeri Pasteur Institute of Iran Tehran, I.R.Iran   The analysis of genetic variation in the malaria vaccine candidate PvMSP-1 gene and evaluation of its immune response 15,000

Renewed grants in vaccine discovery research

Project
ID
Principal Investigator   Institution   Project Title Funding in US$
A10153 Dr Paul Andrew Bates Liverpool School of Tropical Medicine, UK   Testing of vaccines against visceral leishmaniasis 45,000
980455 Professor Ross Leon Coppel Monash University, Clayton, Australia   Malaria protein and gene database 18,200
A10161 Professor Michael Francis Good Queensland Institute of Medical Research, Brisbane, Australia   Targets for malaria cell mediated immmunity from MSP1 and other proteins 45,000
A00265 Dr Weiqing Pan Second Military Medical University, Shanghai, China   Pre-clinical investigation of chimeric protein consisting Plasmodium falciparum AMA-1 and 19kDa C-terminus of MSP1 37,700
A10115 Dr Seyedi Yazdy Sima Rafati Pasteur Institute of Iran, Tehran, Iran Evaluation of immune responses against L. infantum Cysteine proteinases in Kala-azar individuals and DNA vaccinated dogs 35,000

TDR expresses sincere gratitude to members of the Vaccine Discovery Research Committee and external reviewers for their critical assessment and contributions to the selection process.

TDR would also like to thank those investigators who were not funded. A large number of projects were reviewed but only a few selected due to the highly competitive selection process. TDR wishes to encourage these investigators to continue their promising research and to re-compete next year (see deadline for submission of new applications).

TDR contact: Dr R. Ridley

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