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Functional Genomics of Malaria Parasites
An HHMI^[1]/EMBO^[2]/TDR practical course

Overview

Reverse genetic techniques have become proven and essential tools for laboratories studying the biological role of proteins and genes in the malaria parasite.

The aim of this course is to equip participants with the necessary expertise to construct transgenic Plasmodium falciparum (human) and Plasmodium berghei (rodent) parasites and to apply knowledge gained in their home laboratories. 

Who should apply

PhD students and postdoctoral scientists with previous experience in molecular techniques, and a thorough understanding of molecular biology and cell biology - but not necessarily with Plasmodium.

Applications

Sorry but applications have now closed.

Course components

Lectures and practical sessions covering the following topics: 

• Malaria parasites and their genomes 
• Cultivation, transfection and selection of P. falciparum and P. berghei 
• Transfection vector design and construction 
• Use of drug resistance and visual markers 
• Analysis of transgenic parasites 

Faculty

WEHI ^[3], Australia

• Brendan Crabb (Workshop Chair)
• Alan Cowman
• Tania de Koning-Ward
• Paul Gilson
• Alex Maier
• Jennifer Thompson

ICGEB ^[4], India

• Vir Chauhan
• Chetan Chitnis
• Pawan Malhotra

LUMC ^[5], The Netherlands

• Andy Waters

TIGR ^[6], USA

• Malcolm Gardner

Registration

There is no registration fee. Course costs and accommodation will be covered by EMBO/HHMI/TDR

Travel costs 

Participants from developed countries will be expected to bear their own travel expenses. A limited number of travel bursaries will be awarded on a competitive basis to applicants from developing countries, particularly Africa.

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HHMI:       Howard Hughes Medical Institute 
EMBO:     European Molecular Biology Organization 
WEHI:      The Walter and Eliza Hall Institute of Medical Research 
ICGEB:     International Centre for Genetic Engineering and Biotechnology
LUMC:      Leids Universitair Medisch Centrum 
TIGR:        Institute for Genomic Research
FIAT LUX   Alfred University